The sisters first played each other competitively at the Australian Open way back in 1998, with Venus triumphing in straight sets.
Venus closed out the 29th career meeting between the two on her second match point as Serena sailed a forehand long to end the third round match.
The fans' reaction in California came after Venus pulled out of her semifinal with Serena just before the tussle, citing a knee injury. "She just did everything great".
But Serena says she did not watch a single point on the grounds she gets too nervous. "It nearly doesn't matter, but it would just be awesome to see her do it now".
Despite some nerviness and almost squandering a double break lead in the second set, Venus closed it out what was a relatively routine victory. I really abhor every time we play, but I do enjoy the battle when I'm out there. Just when it looked Serena will pave her way back, Venus did not let her.
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Kam Williams has appeared in 10 postseason games, including four starts, averaging 5.8 points and 1.6 rebounds per game. However the Buckeyes tournament stay didn't last long, losing to the Penn State Nittany Lions in the quarterfinals.
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The father of two sets of twins-eight-year-old daughters Myla and Charlene and three-year-old sons Lenny and Leo-said Serena, who launched her comeback at Indian Wells after giving birth to her first child, daughter Alexis Olympia in September, can be the story of the year.
"Obviously, I wish it was anybody else in the draw, literally anybody, but that's OK", Serena said. She made it to round three and faced off against her older sister Venus, 37, on March 12 in a pairing that wowed tennis fans everywhere.
Serena was also booed in the final against Kim Clijsters, a match she won.
Serena has often played her best tennis against her sister because she feels, more than with any other opponent, that she has to. I definitely don't have a favorite match. "The false allegations that our matches were fixed hurt, cut and ripped into us deeply", Serena Williams wrote in a 2015 column published on the website Time.com announcing that would return to the tournament that year, ending a 14-year boycott.
On the men's side, Borna Coric of Croatia upset No. 13 Roberto Bautista Agut of Spain 6-1, 6-3; Jeremy Chardy beat No. 20 Adrian Mannarino 7-5, 4-6, 6-1 in an all-French matchup; and No. 11 Pablo Carreno Busta of Spain defeated Daniil Medvedev of Russian Federation 6-1, 7-5. At a news conference that day, another player was asked who would have won the match between the sisters.