Mikaela Shiffrin rebounded from missing the Olympic slalom podium to clinch her fifth World Cup slalom season title with her 42nd career World Cup victory, most for any racer before turning 23 years old.
Norway's Ragnhild Mowinckel won the race with Germany's Viktoria Rebensburg second.
Her nearest rival, Wendy Holdener of Switzerland, lost any hope of overhauling the United States star when she trailed in 14th on Friday.
Fourth after the first leg, Olympic giant slalom champion Shiffrin rose one place while Swiss Wendy Holdener, the only woman who still had a mathematical chance of depriving her of the title, was back in 14th place.
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Olympic gold and silver medalist Mikaela Shiffrin shows off her medals after her press conference at the Main Press Center.
Shiffrin, 22, becomes only the second American female skier to win multiple overall titles. She previously won gold in slalom, her strongest discipline, at the 2014 Sochi Olympics. A dip in form during her last five races before the Pyeongchang Olympics saw her failing to finish three times and placing seventh twice.
"It's an incredible moment right now", Shiffrin said. She holds a 175-point lead over Petra Vlhova of Slovakia with two races left in the season. "But nothing is impossible so I am going to stay focused". Rebensburg leads the overall giant slalom standings by 92 points over Tessa Worley of France.