Total damage throughout the entire region was still being assessed as of the time of this writing, but the natural disaster had sent Mexico City residents into the street, crowding together for safety.
In Mexico City, where more than 200 people died in a large natural disaster last fall, people streamed out of shaking buildings and into the streets.
Residents said they were terrified when they felt the tremors and saw building swaying for quite some time. Fifteen more people were injured. It had a depth of 43 kilometers.
The quake was initially given a magnitude of 7.5 but was later revised down to 7.2.
Resident Mercedes Rojas Huerta, 57, who was sitting on a bench outside her home in Mexico City said: "It was terrible". "It started to shake; the cars were going here and there".
When addressing the helicopter crash on Twitter, Peña Nieto said there were no reports of fatalities directly linked to the quake and aftershock. In Juchitan, the area hardest hit in the September 7 quake, "no serious damage is reported so far", he said.
The tremor comes five months after the country was rocked by an natural disaster that killed 370 people.
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The powerful, sustained shaking on Friday gave way to 225 aftershocks, the national seismology service said, and caused widespread panic.
A magnitude-7.2 natural disaster sparked panic in Mexico on Friday, five months after hundreds of people were killed in two quakes.
The natural disaster left almost a million homes and businesses without power in Mexico City and the south and damaged at least 50 homes in Oaxaca.
On September 19, an quake measuring 7.1 on the Richter scale devastated Mexico City, causing the collapse of buildings across the metropolis and killing at least 360 people.
"It was terrible", said Mercedes Rojas Huerta, 57.
There is no threat of a tsunami, according to the Pacific Tsunami Warning Centre. "The house is old".