Wenger's men have only the two wins from their last six games, but they do head to the Midlands on the back of Boxing Day's 3-1 victory over Crystal Palace.
Soon after City's game, and hours before Arsenal kicked off, Guardiola said there would be "internal meetings" over whether the club would make a bid for Alexis Sanchez in light of the injury to Jesus.
The Gunners defeated Crystal Palace in a 3-2 victory at Selhurst Park but only four Arsenal players chose to celebrate with Alexis Sanchez after he scored the first goal. "But when? That is very hard to say because it does not depend only on us".
The Chile worldwide is out of contract at the end of the season and will be free to leave the Emirates if no fresh terms are signed. "It will depend on that as well, because we will have to take the consequences of these decisions and respond to it".
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Karanka, who worked alongside Jose Mourinho at Real Madrid, arrives at a club now gripped by the feel-good factor after dumping Arsenal out of the FA Cup at the weekend.
Wenger, who will set a new record of 811 Premier League matches as a manager in the game at The Hawthorns, became frustrated with questions this week over Sanchez's future. I don't know what is going on.
He added: "We have a squad that is equipped to deal with injuries-we've shown that in the Europa League and the Carabao Cup.but we can not lose any more players now".
Battling to hide his fury, Wenger said: "It wasn't a penalty".
Yet the fortune they have been missing surfaced spectacularly when Dean took centre stage a minute from time. "It's hard sometimes when you are paid to talk, to talk, to talk and only say things that are true and intelligent". "We've just come home from West Brom frustrated because we lost two points that were really frustrating".