British police say they are responding to reports of an incident at Oxford Circus subway station, one of London's busiest.
The Reuters witness said the area around the station had been cleared of people and traffic.
London police advised the public in the Oxford Street area to go into buildings while officers worked on the scene.
Police said that at this stage there are not any casualties. The station is now closed, please avoid the area at this time.
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The area remains closed, with British Transport Police officers on the scene.
Armed police are at the scene.
Transport for London have described it as a "customer incident" but it is unclear what this means.
It added: "Officers are responding to reports of an incident at Oxford Circus station".