A statement by Avon & Somerset Police said: "A multi-agency operation is under way on the M5 in South Gloucestershire".
Traffic at a standstill on the M5.
The lorry appeared to have crossed the central reservation from the Southbound carriageway, pictures from the scene showed. I pulled the woman, who I believe is a doctor, out of the auto and she was given two pints of blood on the side of the road before she was taken to hospital.
Major crashes involving multiple fatalities are relatively uncommon in Britain but eight people died in August when two trucks and a minibus collided at the start of a busy bank holiday weekend.
"Our need is to guarantee the casualties' closest relative are advised and upheld, and in addition the progressing administration of the scene, and this imperative work is continuous", he said.
A lady and two kids were additionally harmed in the crash and taken to doctor's facilities in Bristol, where they are in a perilous condition.
Singapore condemns North Korea's latest 'dangerous and brazen provocation'
The South Korean defense ministry said the live-fire ballistic missile drill was approved by President Moon Jae-In. It came on the heels of the adoption of a United Nations resolution imposing harsher sanctions against Pyongyang.
Plunkett and Rashid lead England fight back in Windies T20
While thankful for having won West Indies a trophy off his own bat, Brathwaite's goal now is for consistent global success. We shall anyhow see the return of Chris Gayle , Sunil Narine and Kieron Pollard in the West Indies' national side.
Paul Merson sends warning to N'Golo Kante at Chelsea
Some players joined the club but it is like that in every club. "We know how they play, and we fight to win". We need everyone, especially after our time together in Leicester", the tire-less Frenchman commented.
The lorry driver was taken to clinic to be looked at as a precautionary measure.
Emergency services are at the scene of a serious crash on the M5 in South Gloucestershire.
"I'd also like to thank the members of the public who courageously went to the aid of those involved in this collision and in some cases rescued them from their vehicles".
The motorway is closed in both directions between J16 and J14 - it's expected to remain closed until later tonight.
On Sunday morning, Highways England confirmed the southbound carriageway has re-opened.
This is likely to affect your journey if you are heading up country from Cornwall and you can check the latest information here.