Supreme Leader of the Islamic Revolution Ayatollah Ali Khamenei on Tuesday called Aung San Suu Kyi a "cruel woman" in which crimes against Rohingya Muslims are taking place under her eyes.
Suu Kyi, a Nobel Peace Prize laureate who lived under house arrest for many years under a military junta that ultimately gave way to an elected government, has faced a torrent of worldwide criticism and pressure since the crisis erupted.
The group also demanded that the Bangladesh government put pressure on Myanmar to stop the persecution of Rohingya people.
Ms Suu Kyi has dismissed the Rohingya crisis as a misinformation campaign.
Muslim Rohingya refugees claim Myanmar soldiers sometimes accompanied by Buddhist fighters are forcing them to leave their homes.
Scores of Rohingya civilians have fled to Bangladesh, overwhelming refugee camps that were already bursting at the seams and triggering warnings of a humanitarian crisis.
Myanmar has said it is negotiating with China and Russian Federation to ensure they block any Security Council censure over the crisis.
"The humanitarian situation is catastrophic", Guterres said.
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"We need to prepare for many more to come, I am afraid", said Shinni Kubo, Bangladesh country manager for UNHCR. "Humanitarian agencies are deploying mobile medical teams, installing emergency latrines, providing water, and are distributing tarpaulins for basic shelter and food rations to new arrivals".
In Myanmar, Dujarric said most aid activities in northern Rakhine state remain either suspended or severely interrupted, although the government is delivering some aid through the Red Cross.
A clearance operation by Myanmar's military targeting the Rohingya intensified after 12 security officers were killed by militants in co-ordinated attacks on border posts.
Mamunur Rashid of the International Organization for Migration said the supplies would be enough to help about 5,000 of the roughly 370,000 Rohingya who have arrived in Bangladesh in recent weeks.
Thousands of ethnic Rohingya Muslims have been arriving daily by foot across the swampy border as well as by rickety wooden boats traveling on wild seas since violence erupted on August 25 in Myanmar.
U.S. Ambassador to the United Nations Nikki Haley said the United States was "deeply troubled by continued reports of attacks against innocent civilians and will continue to urge (Myanmar) security forces to respect those civilians as it conducts security operations".
Prime Minister Sheikh Hasina urged Buddhist-majority Myanmar to bring the Rohingya back, while parliament passed a motion Monday night urging the United Nations and other countries to pressure Myanmar for their safety and citizenship.