"With this technology, we can convert skin cells into elements of any organ with just one touch", said Dr Sen.
Results of the trial showed that a week after it was made, blood vessels started appearing in the injured leg.
They say TNT - which is basically a lab on a chip - can adapt skin cells to change into any type of tissue required, which can then be introduced to injured or degenerated areas.
Tests on pigs and mice had a 98 per cent success rate and one procedure saw blood flow to a severely wounded mouse leg restored within a week as the pad reprogrammed skin cells to create vascular cells.
Executive Director of The Ohio State University Comprehensive Wound Center and Director of the Ohio State University's Center for Regenerative Medicine & Cell Based Therapies. So far, there are no known side effects from using TNT, and the treatment takes less than a second. The chip does not stay with you, and the reprogramming of the cell starts. It involves using a nanotechnology-based chip and placing it on the skin of a patient. It could also grow brain cells on human skin under the guidance of a person's immune system, and these cells could then be injected into a person's brain to treat conditions such as Alzheimer's and Parkinson's disease.
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Chandan Sen, director of the Center for Regenerative Medicine and Cell-Based Therapies, said that now, the technology not only works on skin cells, but can also fix other types of tissue. The second is the design of the particular biological cargo for cell conversion.
The Ohio State University researchers have developed a new device that they claim can heal organs with just a single touch. "The difference with our technology is how we deliver the DNA into the cells".
It instantly delivers new DNA or RNA into living skin cells to change their function, with a small electrical charge that's barely felt by the patient, thus aiding the speedy fix of injured tissue as well as restoring the function of ageing tissue, including organs. They believe it will be possible to reprogram skin cells to harvest brain cells in a peripheral part of the body, such as the arm, which can then be injected into the brain.
The concept is very simple, adds co-author James Lee: "As a matter of fact, we were even surprised how it worked so well". For a long time researchers have tried to come up with a mechanism that could treat and even fix brain injuries.